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KMID : 1059520120560040459
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Journal of the Korean Chemical Society
2012 Volume.56 No. 4 p.459 ~ p.463
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Synthesis of New 8-Formyl-4-methyl-7-hydroxy Coumarin Derivatives
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Manidhar D. M.
Rao K. Uma Maheswara
Reddy N. Bakthavatchala
Sundar Ch. Syama
Reddy C. Suresh
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Abstract
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8-Formyl-4-Methyl-7-Hydroxy Coumarin Derivatives were synthesized via Penchem condensation followed by Duffs reaction. Treatment of this with N,N-di substituted cyano acetamides in the presence of piperdine afforded New 8- Formyl-4-Methyl-7-Hydroxy Coumarin Derivatives (7a-o). Their structures were characterized by IR, 1H and 13C NMR and Mass spectral and elemental analysis data.
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KEYWORD
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N,N-di substituted cyano acetamides, Piperdine, Coumarin derivatives
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